Help & Feedback
About DbCAS
DbCAS was created to address a growing challenge in the RNA splicing field: the rapid expansion and fragmentation of alternative-splicing databases across platforms, organisms, technologies, and analytical frameworks. As long-read sequencing, single-cell profiling, and context-specific transcriptomics accelerate, researchers increasingly struggle to locate, compare, and contextualize the resources most relevant to their work. DbCAS brings these datasets together into a single, coherent commons, making navigation and discovery easier and the landscape more transparent for the RNA splicing community.
DbCAS was built through a systematic literature-mining workflow that began with 16,212 splicing-related publications retrieved across 2014–2026. Backward citation expansion and identity-based deduplication expanded the candidate pool to 383,439 publications. Keyword filtering, two model-assisted screening steps, and evidence-based website verification produced a curated collection of 287 databases covering 109 species/taxa. DbCAS will continue to monitor resource accessibility and update the collection regularly.
This initiative is led by Dr Kif Liakath-Ali and the SpliceLab at the University of Southampton, with the goal of supporting open, accessible, and integrative RNA splicing research worldwide.
Classification Standard
DbCAS organizes resources into four major classes and 12 subcategories. Select an example to open the corresponding database.
II. Core Splicing Outcome Resources
II_1 Alternative Splicing Event
II_2 Splice-Site and Junction
III. Indirect Splicing Regulation Resources
III_1 Splicing-Regulator
III_2 Variant and Splicing-Effect
IV. Specialized RNA Processing and Noncanonical Transcript Resources
IV_1 circRNA
IV_2 Chimeric and Fusion Transcript
IV_3 lncRNA Transcript and Isoform
IV_4 NMD-Related Transcript
IV_5 Alternative Polyadenylation and 3′-End Processing
IV_6 Other Specialized RNA Splicing and Cleavage
Feedback and Contribute
Have a database to add? We'd love to hear from you!
DbCAS is a community-driven resource, and we welcome your contributions. If you maintain an alternative-splicing database or know of a resource that is missing from our catalogue, we would be delighted to include it. Please reach out with the database name, link, publication and a brief description, we will add it to DbCAS.
Upload information for your database: Adding New Database to DbCAS
Contact: Dr Kif Liakath-Ali
