About

About DbCAS

DbCAS was created to address a growing challenge in the RNA splicing field: the rapid expansion and fragmentation of alternative splicing databases across platforms, organisms, technologies, and analytical frameworks. As long-read sequencing, single-cell profiling, and context-specific transcriptomics proliferate, researchers increasingly struggle to locate, compare, and contextualise the resources most relevant to their work. DbCAS brings these resources together in a single, coherent commons — making navigation and discovery easier and the landscape more transparent for the splicing community.

DbCAS was built through a systematic literature-mining workflow that began with 16,212 splicing-related publications retrieved across 2014–2026. Backward citation expansion and identity-based deduplication grew the candidate pool to 383,439 publications, from which keyword filtering, two model-assisted screening steps, and evidence-based website verification produced a collection of 382 databases covering 166 species and taxa. Main highlights recommended databases, while Full includes every database, including currently inaccessible resources. Resource accessibility is monitored continuously, and the collection is updated regularly.

This initiative is led by Dr Kif Liakath-Ali, Principal Investigator of SpliceLab, University of Southampton, with the goal of supporting open, accessible, and integrative RNA splicing research worldwide.